SECONDARY METABOLITES PRODUCTION THROUGH BIOTECHNOLOGICAL INTERVENTION: A REVIEW

Sekh Abdul Nasim; Junaid Aslam; Rashmi Kapoor; Saeed Ahmad Khan

doi:10.9755/ejfa.v22i3.4886

Authors

Sekh Abdul Nasim Hamdard University, India; Dubai Pharmacy College,UAE
Junaid Aslam Department of Botany, Faculty of Science, Hamdard University, New Delhi-110062, India; Plant Tissue Culture Laboratory, Dubai Pharmacy College, Al-Muhaisanah 1, Al Mizhar, P.O. Box 19099, Dubai, United Arab Emirates;
Rashmi Kapoor Department of Botany, Faculty of Science, Hamdard University, New Delhi-110062, India
Saeed Ahmad Khan Department of Pharmaceutical and Medicinal Chemistry, Dubai Pharmacy College, Al-Muhaisanah 1, Al Mizhar, P.O. Box 19099, Dubai, United Arab Emirates

DOI:

https://doi.org/10.9755/ejfa.v22i3.4886

Keywords:

Plant Tissue Culture, secondary metabolites, alliin, artimisnin, podophyllotoxin, taxol

Abstract

The plants used in the phyto-pharmaceutical preparations are obtained mainly from the natural growing areas. With the increasing demand for the crude drugs, the plants are being overexploited, threatening the survival of many rare species. In addition, agriculture land decreasing day by day due to the real estate, industrialization, and roads for the betterment of human beings. To maintain the required demand of the important secondary metabolites and their sources; several research institutions and pharmaceutical industries using advanced biotechnological tools, this includes culturing of plant cells, genetic manipulation aiming to restore the germplasm, insertion of interest of genes for the production of important active principle. The present 2 covering the in vitro micropropagation and production of selected secondary metabolites through biotechnological intervention viz. Alliin, Artimisnin, Podophyllotoxin, and Taxol.